Now showing items 1-6 of 6

    • Jalil Milad, Jorge; Córdova, Samuel; Piddo Mijares, Ana María; Chamorro, Gastón; Braun J., Sandra; Vega, Jeanette; Jadue, Liliana; Lavandero González, Sergio; Jalil R., R.; Lastra, P.; Garrido, Carmen (Sociedad Chilena de Cardiología y Cirugía Cardiovascular, 2000)
      El objetivo del estudio fue estimar la prevalencia de los distintos alelos del polimorfismo del gen de la enzima convertidora de angiotensina (ECA), inserción/deserción (I/D) y simultáneamente la actividad de ECA plasmática ...
    • Jalil Milad, Jorge; Córdova, Samuel; Ocaranza, María Paz; Schumacher, Erwin; Braun J., Sandra; Chamorro, Gastón; Fardella, Carlos E.; Lavandero González, Sergio (International Medical Science for Experimental and Clinical Research, 2002)
      The insertion/delection ACE polymorphism (ACE I/D) regulates different levels of circulating and tissue ACE activities, which may induce diverse adrenergic responses to physiological stimuli. The aim of this study was ...
    • Gabrielli, Luigi A.; Winter, José L.; Godoy, Iván; McNab, Paul; Padilla, Ivonne; Córdova, Samuel; Rigotti, Paola; Novoa, Ulises; Mora, Italo; García Nannig, Lorena; Ocaranza, María P.; Jalil Milad, Jorge (Oxford University Press, 2014)
      background There is experimental evidence on the role of Rho-kinase (ROCK) activation in cardiac hypertrophy but no information on its role in human hypertension and left ventricular hypertrophy (LVH). We hypothesized that ...
    • Ocaranza, María Paz; Gabrielli, Luigi; Mora, Italo; García Nannig, Lorena; McNab, Paul; Godoy, Iván; Braun, Sandra; Córdova, Samuel; Castro, Pablo; Novoa, Ulises; Chiong Lay, Mario; Lavandero González, Sergio; Jalil, E. (MOSBY-ELSEVIER, 2011-05)
      Background The small guanosine triphosphatase Rho and its target Rho-kinase have significant roles in experimental remodeling and ventricular dysfunction, but no data are available on Rho-kinase activation in patients with ...
    • Jalil Milad, Jorge; Piddo Mijares, Ana María; Córdova, Samuel; Chamorro, Gastón; Braun J., Sandra; Jalil, R.; Vega, J.; Jadue, P. L.; Lavandero González, Sergio; Lastra, P. (ELSEVIER SCIENCE INC, 1999-07)
      The aim of this study was to estimate the prevalence of the different alleles of the angiotensin converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and associated plasma ACE activity, as well as cardiac ...
    • Ocaranza, María Paz; Moya, Jackeline; Jalil, Jorge E.; Lavandero González, Sergio; Kalergis, Alexis M.; Molina, Cristián; Gabrielli, Luigi; Godoy, Iván; Córdova, Samuel; Castro, Pablo; Mac Nab, Paul; Rossel Mariángel, Víctor; García, Lorena; González, Javier; Mancilla, Cristián; Fierro, Camila; Farías, Luis (Wiley, 2020)
      Background: Increased Rho-kinase activity in circulating leucocytes is observed in heart failure with reduced ejection fraction (HFrEF). However, there is little information in HFrEF regarding other Rho-kinase pathway ...